Perhaps if the longer duration of a race cam in four-strokes or porting in two strokes, gives better cylinder filling, so combustion pressures are already higher than they are with standard cams ? With most cams and porting regimes, there is a well defined power band which is always the same regardless of measured compression ratio. In a 7 to 1 comp. engine, the power band in terms of RPM, is exactly the same as in a 10 to 1 comp. engine. The standing waves in the inlet tract and the exhaust do not change, they are set by the timings and the lengths of the tubes. All that happens when you raise the comp. is you increase the pressure in the combustion chamber, so the temperature of the combustion process rises, so you need more fuel to maintain the balance between ignition advance and the higher compression - that is where the extra power comes from. If you are using higher comp., it is common practice to use less ignition advance, so the advantage of higher comp. can be largely negated. With race cams, you usually get more power right across the whole rev range, but much more above the point at which the cam really starts to work. With a lower comp. motor, you can get more power by running it leaner and getting optimum combustion conditions, because jetting is not so critical with the lower combustion pressure.
I have a friend who used 14 to 1 comp. in his Manx with methanol fuel. The pistons used to collapse under the inlet valve, even though he had retarded the ignition by 4 degrees.