How do you accurately measure the 25% at home in your home garage ? With methanol, the less time you have your can open, the better - it takes up moisture. Years ago, many service stations had a manual pump which used to dispense a measured amount of fuel from a glass container. I would not try to mix using measuring cylinders - you would be exposed to all the risks.
Of all people, I am probably better equipped to blend fuels, but I would not do it at home. I also probably have more to gain by using a blend, than most other people. With straight methanol, there are no complications - as long as you drain the carbs after every race meeting.
What really surprised me was that by using straight methanol, my 850 motor is quick enough to win against some pretty formidable opposition, even with low comp. It really has not had much done to it. The cam and ignition timing are advanced and it has a 2 into 1 exhaust. Without methanol, I would probably not be able to do that. The exhaust system or a piston might melt.
The only real problem the bike has got, is that it is too loud.